The purpose of this article is to describe the process of 4 cannabinoid drugs you should need to know

We have all heard of the benefits of medical marijuana, but why is it not approved by the US Food and Drug Administration (FDA)?

The truth is that for a drug to be approved by the FDA, clinical trials with hundreds of thousands of people must have been conducted to determine the benefits and risks of the drug. In the case of marijuana (without referring to cannabinoids), there are not enough clinical trials to show all their effects, according to data from the National Institute on Drug Abuse (NIH). However, we do know the effects of cannabinoids present in the marijuana plant, especially Cannabidiol (CBD).

Cannabinoid Drugs

Know all about  Cannabidiol (CBD) 

What are cannabinoids?

Cannabinoids are organic chemicals capable of activating the cannabinoid receptors present in the body and brain of animals. It is a group of substances very broad and diverse, but with a similar chemical structure, characterized by being carbocyclic and formed by 21 carbon atoms.

From the study of cannabinoids, a number of drugs have already been approved by the FDA, taking advantage of the therapeutic benefits of these and minimizing or eliminating harmful side effects.

Many may not know these drugs and the effects of each of them, so we present below a list of the 4 most important Cannabinoid Drugs , along with their medicinal effects.

Here’s a brief rundown of the 4 cannabinoid drugs working their way through clinical and preclinical trials.

  1. Dronabinol (Marinol®)

This drug contains cannabinoid called Dronabinol (Delta-9-tetrahydrocannabinol synthetic) and is used to treat loss of appetite associated with weight loss in acquired immunodeficiency syndrome (AIDS), and for nausea and vomiting associated with Cancer chemotherapy in patients who have not responded adequately to conventional treatments to relieve nausea and vomiting.

  1. Nabilone (Cesamet®)

This drug contains cannabinoid called Nabilone and is primarily used to help relieve nausea or vomiting caused by chemotherapy. It is for people who continue to feel nauseous or vomiting even if they have already taken medications to treat these symptoms.

  1. Sativex®

This drug contains the cannabinoids THC and CBD, approximately in the same proportion. This drug is used to treat symptoms related to multiple sclerosis such as muscle stiffness or spasticity and pain.

  1. Epidiolex ™

The latter is a patented oral solution of cannabidiol derived from pure plants, or CBD. It is currently undergoing clinical trials to establish its efficacy and safety, aimed mainly at people with severe epilepsy, Dravet syndrome, Lennox-Gastaut syndrome (LGS), Tuberous Sclerosis Complex (TSC) or infantile spasms.

It should be remembered that the drugs mentioned in the list are synthetic and it is recommended to consult a specialist before trying any of them.

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